MASS TORT CLAIMS:
WHAT IS A XARELTO?
Xarelto is the first once-a-day blood thinner, or anticoagulant, approved by the FDA. It was designed to reduce the risk of a blood clot after a major surgery such as a hip or knee replacement, to reduce the risk of a stroke from atrial fibrillation, and to treat and reduce the risk of DVT (Deep Vein Thrombosis).
HOW DOES XARELTO WORK?
Like other blood thinners, Xarelto works by affecting a specific protein found in blood called Factor Xa. Factor Xa’s main job is to start the clotting process when the body needs it. Xarelto blocks Factor Xa and stops the production of the clotting enzyme called thrombin. This is what essentially stops blood clots from forming.
WHY CHOOSE XARELTO?
The original blood thinner in pill form is Warfarin. While Warfarin works to also thin blood, it requires close monitoring of dosage, diet, and must be taken multiple times a day. When Xarelto hit the market, its claim to fame was that it was a once-a-day drug and no additional monitoring was needed, allowing patients to live more freely. However, for some patients taking Xarelto, uncontrollable internal bleeding can take place.
IS THERE AN ANTIDOTE FOR XARELTO?
Unfortunately, unlike Warfarin, there is no antidote for Xarelto. Within the first year on the market, 2,081 “Serious Adverse Event” reports were filed with the FDA and of those, 151 were deaths. If hemorrhagic complications arise during Xarelto use, there is no reversal agent. The original packaging in the U.S. did not contain a warning label but briefly mentioned it in the Overdosage section.
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